Mapping the DNA-Binding Motif of Scabin Toxin, a Guanine Modifying Enzyme from Streptomyces scabies
نویسندگان
چکیده
منابع مشابه
Dynamics of Scabin toxin. A proposal for the binding mode of the DNA substrate
Scabin is a mono-ADP-ribosyltransferase enzyme and is a putative virulence factor produced by the plant pathogen, Streptomyces scabies. Previously, crystal structures of Scabin were solved in the presence and absence of substrate analogues and inhibitors. Herein, experimental (hydrogen-deuterium exchange), simulated (molecular dynamics), and theoretical (Gaussian Network Modeling) approaches we...
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ژورنال
عنوان ژورنال: Toxins
سال: 2021
ISSN: 2072-6651
DOI: 10.3390/toxins13010055